Αρχική σελίδα ΣΥΓΓΡΑΦΙΚΟ ΕΡΓΟ-ΔΙΕΘΝΕΙΣ ΔΗΜΟΣΙΕΥΣΕΙΣ Contraindications of sentinel lymph node biopsy: are there any really?
Contraindications of sentinel lymph node biopsy: are there any really? Εκτύπωση E-mail


Filippakis GM, Zografos G. World J Surg Oncol. 2007 Jan 29;5:10.
Θεματολογία: Γενική Χειρουργική – Μαστός / Λεμφαδένας Φρουρός – Κλινική
Μεθοδολογία: Αναφορά Βιβλιογραφίας
Αριθμός Ατόμων: -
Αναφορές (Citations): Google Scholar: 12, Scopus:1
Συντελεστής Απήχησης(Impact Factor): 1.00
Το συγκεκριμένο άρθρο υπήρξε το πρώτο τρίμηνο της δημοσίευσης του στα πλέον πολυδιαβασμένα άρθρα του BioMed Central και χαρακτηρίστηκε ως Highly Accessed.”

Abstract

BACKGROUND: One of the most exciting and talked about new surgical techniques in breast cancer surgery is the sentinel lymph node biopsy. It is an alternative procedure to standard axillary lymph node dissection, which makes possible less invasive surgery and side effects for patients with early breast cancer that wouldn't benefit further from axillary lymph node clearance. Sentinel lymph node biopsy helps to accurately evaluate the status of the axilla and the extent of disease, but also determines appropriate adjuvant treatment and long-term follow-up. However, like all surgical procedures, the sentinel lymph node biopsy is not appropriate for each and every patient. METHODS: In this article we review the absolute and relative contraindications of the procedure in respect to clinically positive axilla, neoadjuvant therapy, tumor size, multicentric and multifocal disease, in situ carcinoma, pregnancy, age, body-mass index, allergies to dye and/or radio colloid and prior breast and/or axillary surgery. RESULTS: Certain conditions involving host factors and tumor biologic characteristics may have a negative impact on the success rate and accuracy of the procedure. The overall fraction of patients unsuitable or with multiple risk factors that may compromise the success of the sentinel lymph node biopsy, is very small. Nevertheless, these patients need to be successfully identified, appropriately advised and cautioned, and so do the surgeons that perform the procedure. CONCLUSION: When performed by an experienced multi-disciplinary team, the SLNB is a highly effective and accurate alternative to standard level I and II axillary clearance in the vast majority of patients with early breast cancer.

Cited by:
1. Measurement of Uterine Radiation Exposure from Lymphoscintigraphy Indicates Safety of Sentinel Lymph Node Biopsy during Pregnancy. Philip M. Spanheimer1, Michael M. Graham2, Sonia L. Sugg1, Carol E. H. Scott-Conner1 and Ronald J. Weigel. Annals of Surgical Oncology March 07, 2009.
2. Lymphoscintigraphy in breast cancer: a short review about the impact on upper limb after surgical treatment. Anke BergmannI; Juliana Miranda Dutra de ResendeI; Sebastião David Santos-FilhoII; Marcelo Adeodato BelloI; Juliana Flavia de OliveiraI; Christopher J. PalestroIII; Mario Bernardo-Filho. Braz. arch. biol. technol. vol.51 no.spe Curitiba Dec. 2008
3. Accuracy of fine-needle aspiration cytology of axillary lymph nodes in breast cancer patients. Einas Alkuwari, MD, Manon Auger, MD. Cancer Cytopathology Volume 114 Issue 2, Pages 89 – 93
4.Selective sentinel lymph node biopsy and primary systemic therapy in breast cancer. Antonio Piñero, Julia Giménez, Sergi Vidal-Sicart, and Mattia Intra Tumori, 96: 17-23, 2010.
5. Sentinel Lymph Node Dissection in Vulvar Carcinoma: What Is the Acceptable False-Negative Rate? Bradley J. Monk, MD. Oncology. Vol. 22 No. 5, 2008.
6. Use of PCR to Evaluate Axillary Node Status in Breast Cancer. McCarty, Kenneth S. Jr MD, PhD; Silver, Susan A. MD. Pathology Case Reviews: May/June 2008 - Volume 13 - Issue 3 - pp 95-98.
7. Sentinel Node Mapping: Status in 2008. Howard-McNatt, Marissa MD; Levine, Edward A. MD. Pathology Case Reviews: May/June 2008 - Volume 13 - Issue 3 - pp 87-94.
8. Selective sentinel lymph node biopsy and primary systemic therapy in breast cancer.  Antonio Piñero, Julia Giménez, Sergi Vidal-Sicart, Mattia Intra. Tumori Vol.96, No1-2010.
9. Invasive Vulvar Cancer in Pregnancy: Case Report and Current Literature Review. Journal of Lower Genital Tract Disease: October 2009 - Volume 13 - Issue 4 - pp 264-268.
10. Optimización de la biopsia selectiva de ganglio centinela en el cáncer de mama mediante palpación axilar intraoperatoria. JS Vicente. Revista Española de Medicina Nuclear, 2010
11. Ganglion Sentinela Y Cancer de Mama. Juan de Dios Díaz-Rosales, MD. Rev Electron Biomed / Electron J Biomed 2009;1:40-45.
12. Breast Cancer during pregnancy following breast augmentation: a case report. Journal of the Japanese Surgical Sociaty. Vol70(2009), No11, p:3259-3262.

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